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College of Medicine - Faculty Development: Faculty Retreat 2017
The theme of the Annual Faculty Retreat for HUCM is Innovating and Updating the Medical School Curriculum. Despite wide consensus on needed changes in medical education, experts agree that the gap continues to widen between how physicians are trained and the future needs of our health care system. A new model for medical education is needed to create the medical school of the future. This retreat aims to provide a framework around successful innovation and updating existing medical school curricula. Please contact the Office of Faculty Developmentif you have any questions.
Swati Jain Goel, MD, Assistant Dean, Office of Faculty Development
The $1,000 Genome by Kevin DaviesIn 2000, President Bill Clinton signaled the completion of the Human Genome Project at a cost in excess of $2 billion. A decade later, the price for any of us to order our own personal genome sequence—a comprehensive map of the 3 billion letters in our DNA—is rapidly and inevitably dropping to just $1,000. Dozens of men and women—scientists, entrepreneurs, celebrities, and patients—have already been sequenced, pioneers in a bold new era of personalized genomic medicine. The $1,000 genome has long been considered the tipping point that would open the floodgates to this revolution. Do you have gene variants associated with Alzheimer’s or diabetes, heart disease or cancer? Which drugs should you consider taking for various diseases, and at what dosage? In the years to come, doctors will likely be able to tackle all of these questions—and many more—by using a computer in their offices to call up your unique genome sequence, which will become as much a part of your medical record as your blood pressure. Indeed, many experts are advocating that all newborns have a complete genome analysis done so that preventive measures and preemptive medicine can begin early in life. How has this astonishing achievement been accomplished? And what will it mean for our lives? To research the story of this unfolding revolution, critically acclaimed science writer Kevin Davies has spent the past few years traveling to the leading centers and interviewing the entrepreneurs and pioneers in the race to achieve the $1,000 genome. He vividly brings to life the extraordinary drama of this grand scientific achievement, revealing the masterful ingenuity that has transformed the process of decoding DNA and delivering the information it possesses to the public at large. Davies also profiles the future of genomic medicine and thoughtfully explores the many pressing issues raised by the tidal wave of personal genetic information. Will your privacy be protected? Will you be pressured, by insurance companies or by your employer, to get your genome sequenced? What psychological toll might there be to discovering you are at risk for certain diseases like Alzheimer’s? And will the government or the medical establishment come between you and your genome? One thing that is not in question is that we are moving swiftly into the personalized medicine era, and The $1,000 Genome is an essential guide to this brave new future.
Toward Precision Medicine by National Research CouncilMotivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.
Out of the Flames by Lawrence Goldstone; Nancy Bazelon GoldstoneMichael Servetus is one of those hidden figureheads of history who is remembered not for his name, but for the revolutionary deeds that stand in his place. Both a scientist and a freethinking theologian, Servetus is credited with the discovery of pulmonary circulation in the human body as well as the authorship of a polemical masterpiece that cost him his life. The Chrisitianismi Restituto, a heretical work of biblical scholarship, written in 1553, aimed to refute the orthodox Christianity that Servetus' old colleague, John Calvin, supported. After the book spread through the ranks of Protestant hierarchy, Servetus was tried and agonizingly burned at the stake, the last known copy of the Restitutio chained to his leg. Servetus's execution is significant because it marked a turning point in the quest for freedom of expression, due largely to the development of the printing press and the proliferation of books in Renaissance Europe. Three copies of the Restitutio managed to survive the burning, despite every effort on the part of his enemies to destroy them. As a result, the book became almost a surrogate for its author, going into hiding and relying on covert distribution until it could be read freely, centuries later. Out of the Flames tracks the history of this special work, examining Servetus's life and times and the politics of the first information during the sixteenth century. Lawrence and Nancy Goldstone follow the clandestine journey of the three copies through the subsequent centuries and explore its author's legacy and influence over the thinkers that shared his spirit and genius, such as Leibniz, Voltaire, Rousseau, Jefferson, Clarence Dorrow, and William Osler. Out of the Flames is an extraordinary story providing testament to the power of ideas, the enduring legacy of books, and the triumph of individual courage. From the Hardcover edition.