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Cardiology: Morning and Noon Conference

Morning and Noon Conference

February 2020

Alzheimer's Disease and Dementia: Role of Cardiovascular Disease Risk, Thomas Obisesan, MD, MPH. 2/25/20

2015 Alzheimer's disease facts and figures.

https://www.ncbi.nlm.nih.gov/pubmed/25984581

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819840/

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958625/

Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667653/

High blood pressure, hypertension, and high pulse pressure are associated with poorer cognitive function in persons aged 60 and older: the Third National Health and Nutrition Examination Survey.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614341/

Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies.

https://www.clinicalkey.com/#!/content/playContent/1-s2.0-S147444221930393X?returnurl=null&referrer=null

Associations of Pulse and Blood Pressure with Hippocampal Volume by APOE and Cognitive Phenotype: The Alzheimer's Disease Neuroimaging Initiative (ADNI).

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143389/

Physical activity and dementia: The need for prevention trials.

https://journals.lww.com/acsm-essr/Fulltext/2007/01000/Physical_Activity_and_Dementia__The_Need_for.6.aspx

Physical activity and risk of cognitive impairment and dementia in elderly persons.

https://jamanetwork.com/journals/jamaneurology/fullarticle/778849

A prospective study of physical activity and cognitive decline in elderly women: women who walk.

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/648735

Fitness effects on the cognitive function of older adults: a meta-analytic study.

https://journals.sagepub.com/doi/pdf/10.1111/1467-9280.t01-1-01430

Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial.

https://jamanetwork.com/journals/jama/fullarticle/182502

APOEε4 impacts up-regulation of brain-derived neurotrophic factor after a six-month stretch and aerobic exercise intervention in mild cognitively impaired elderly African Americans: A pilot study.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193139/

A standardized randomized 6-month aerobic exercise-training down-regulated pro-inflammatory genes, but up-regulated anti-inflammatory, neuron survival and axon growth-related genes.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553116/

The role of insulin receptor signaling in the brain.

https://www.ncbi.nlm.nih.gov/pubmed/15734146

Efficacy and Safety of Plasma Exchange with 5% Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-β Concentrations and Cognition Outcomes in Alzheimer's Disease Patients: A Multicenter, Randomized, Controlled Clinical Trial.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240541/

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